Molecular Docking Studies of Glycyrrhizic Acid (GA), Glycyrrhetic Acid (GE) and Glabridin (GLA) with Estrogen Receptors (ERs)
نویسندگان
چکیده
منابع مشابه
Extraction of Glycyrrhizic Acid and Glabridin from Licorice
The extraction and separation conditions of glycyrrhizic acid and glabridin from licorice were investigated. By changing the different extraction solvents, procedures, times and temperature, the optimum extraction condition was established: the used of ethanol/water (30:70, v/v) as an extraction solvent, and 60 min dipping time under 50 degrees C. The extracts of licorice were separated and det...
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برهمکنش dnaتیموس گاوی طبیعی (ct-dna) با اتیلن دی آمین تترااستات (edta)در بافرtris-hcl با 8/7 ph ( دراین ph،edta به نمک دی سدیم تبدیل می شود) وسسامول در بافر tris-hcl با4/7 ph مورد بررسی قرار گرفته است. edta و سسامول استفاده فراوانی در تکنولوژی غذایی و صنعت شیمیایی دارند. مدل اتصال dna مربوط بهedta بوسیله اسپکتروفتومتری جذب، دورنگ نمایی حلقوی(cd)، ویسکومتری وژل الکتروفورز بررسی شده است. طیفuv ...
15 صفحه اولEffect of Glabridin and Glycyrrhizic Acid on Histomorphometric Parameters of Bones in Ovariectomized Rats.
Licorice is a medicinal plant showing many therapeutic activities. Its roots contain numerous pharmacologically active compounds such as a triterpenoid saponin--glycyrrhizic acid and an isoflavan--glabridin. There are reports indicating that glabridin exhibits estrogen-like activity, therefore it can be classified into phytoestrogens, which may soothe menopause symptoms including postmenopausal...
متن کاملMolecular Docking Studies of Some Novel Hydroxamic Acid Derivatives
A series of few triazole linked hydroxamic acid derivatives were designed virtually considering the basic pharmacophore of suberoyl anilide hydroxamic acid (SAHA). The least energy conformers of each molecule was generated and docked with human histone deacetylase (HDAC8) with PDB id 1T69 using Autodock 4.0.1. Most of the molecules have shown significant binding interaction with the receptor. A...
متن کاملTreatment of Hematological Malignancies with Glycyrrhizic Acid.
The current study examined the effectiveness of glycyrrhizic acid (GA) in reducing cell viability and inducing apoptosis in human chronic myeloid leukemia (CML) in vitro and a mouse lymphoma in vivo. Additionally, we assessed GA as a candidate for combinational therapy in CML along with the current frontline treatment, imatinib (IM). Treatment of K562 CML cells with GA alone resulted in signifi...
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ژورنال
عنوان ژورنال: Biosciences, Biotechnology Research Asia
سال: 2017
ISSN: 0973-1245,2456-2602
DOI: 10.13005/bbra/2411